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PECULIARITIES AND MECHANISMS OF DEVELOPMENT OF CERTAIN FORMS OF ALLERGIC REACTIONS, INCLUDING HYPERSENSITIVITY OF CELLULAR AND HUMORAL TYPES. CONTACT DERMATITIS

Volkov Kirill Andreevich  (Laboratory Assistant, Department of Clinical Medicine, N.G. Chernyshevsky Saratov National Research State University; Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia)

Afanasyeva Galina Alexandrovna  (Doctor of Medical Sciences, Professor, Head of the Department of Pathological Physiology named after Academician A.A. Bogomolets, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia)

Polutova Natalia Vasilyevna  (Candidate of Medical Sciences, Associate Professor, Associate Professor of the Department of Pathologic Physiology named after Academician A.A. Bogomolets, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia)

Polidanov Maxim Andreevich  (research department specialist, assistant of the Department of Biomedical Disciplines, Private University «Reaviz», Saint Petersburg, Russia)

Polutov Vadim Eduardovich  (Assistant of the Department of Pediatric Dentistry and Orthodontics, Saratov State Medical University named after V.I. Razumovsky, Saratov, Russia)

Allergy of this type occurs more often to low molecular weight substances of organic and inorganic origin: various chemicals, paints, varnishes, cosmetics, antibiotics, pesticides, arsenic, cobalt, platinum compounds affecting the skin. Contact dermatitis can also cause substances of plant origin - cotton seeds, citrus fruits. Allergens, penetrating into the skin, form stable covalent bonds with SH- and NH2-groups of skin proteins. These conjugates have sensitizing properties.

Keywords:allergy, contact dermatitis, sensitization, antigens, graft.
 

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Citation link:
Volkov K. A., Afanasyeva G. A., Polutova N. V., Polidanov M. A., Polutov V. E. PECULIARITIES AND MECHANISMS OF DEVELOPMENT OF CERTAIN FORMS OF ALLERGIC REACTIONS, INCLUDING HYPERSENSITIVITY OF CELLULAR AND HUMORAL TYPES. CONTACT DERMATITIS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№03. -С. 161-164 DOI 10.37882/2223-2966.2025.03.13
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