FEATURES OF THE COURSE OF MYASTHENIC CRISIS IN LATE-DEBUTING DISEASE

Chudopal Sergei Michailovich, Ulimbasheva Emma Sufyanovna, Sabanchieva Zhaneta Khuseinovna, Deshev Astemir Leonidovich, Poroshina Amina Abdulselimovna, Tatimova Ellina Latmirovna

Myasthenia gravis according to modern concepts is a heterogeneous group of autoimmune pathology with a postsynaptic neuromuscular transmission defectsts and can be classified by the prevalence of the lesion, the detection of specific antibodies, the age at onset of the disease, the presence of thymus pathology. Such a clinico-pathogeneticheterogencity creates difficulties in the diagnostics and treatment of the disease. With late (over 50 years) myasthenia gravis debilily, the disease often has flow characteristics: a predominat lesion of bulbar musculature, a severe progressive course, a lack of proper effect from the therapy. If in patients with myastenia gravis of older age there is vascular load, then it is often mistakenly diagnosed with cerebral stroke. Presented case severe generalized myasthenia gravis with bulbar syndrome in a patient of 60 years old, shows the features of the cours of this disease with late debute. Key words: myasthenia gravis, myasthenic crisis, late onset, case report.

Keywords:myasthenia gravis, myasthenic crisis, late onset, case report.