RISK FACTORS FOR ASCENDING AORTIC DILATION IN PATIENTS WITH SERONEGATIVE SPONDYLARTHRITIDES

Bogatyreva Valentina Aleksandrovna, Morova Natalia Aleksandrovna

The article presents the results of a study that evaluated the frequency of ascending aortic dilation in patients with seronegative spondyloarthritides and identified the factors that influence its development. The article also analyzes the relationship between ascending aortic diameter and electrocardiographic intervals in patients with seronegative spondyloarthritides. Materials and methods. The study involved 120 patients with seronegative spondyloarthritides who were treated at the Rheumatology Department of the Omsk Regional Clinical Hospital. All patients underwent 12-lead electrocardiography and echocardiography. 26 (21.7%) of the 120 patients had an enlarged ascending aorta. There was no statistically significant association between HLA B27 gene carriage, disease activity, type of medical therapy, and aortic dilation. The analysis of correlation relationships showed a dependence between the expansion of the ascending aorta and height (r=-0.4, p=0.000005), weight (r=0.4, p=0.000079), age of patients (r=0.5, p=0.000000), and duration of the disease (r=0.3, p=0.013402). The expansion of the ascending aorta in patients with seronegative spondylarthritises was associated with the presence of arterial hypertension (p(U) = 0.0445). The relationship between cardiac rhythm and conduction disorders and the condition of the aorta was analysed.

Keywords:seronegative spondylarthritides, ankylosing spondylitis, psoriatic arthritis, aortitis, ascending aortic dilation, cardiac conduction disorders, and risk factors.