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Effects of local hypothermia on spinal cord injury in dogs

Yafarova G. G.  (Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420006, Russia GAUZ «Republica Klinical Hospital» RT, Kazan, Russia )

Kadysheva E.   (Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420006, Russia)

Baltina T. V.  (Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan 420006, Russia)

The goal of this study was to estimate the influence of local hypothermia on spinal cord condition after contusion. In this study we investigated morphological and structural changes in dogs spinal cord 10 days after a spinal cord contusion with and without local hypothermia applied in acute period (20 minutes after contusion) and also in control animals (with laminectomia). Our results shown that local hypothermia in acute period after spinal cord contusion may have neuroprotective effect and prevent from development of secondary traumatic changes such as apoptosis and inflammation.

Keywords:Spinal cord injury, hypothermia, apoptosis, inflammation
 

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Citation link:
Yafarova G. G., Kadysheva E. , Baltina T. V. Effects of local hypothermia on spinal cord injury in dogs // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2015. -№12. -С. 14-18
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