Fateeva Anastasia (post-graduate student of the I.M.Sechenov
First Moscow State Medical University
at the Department of Endocrinology of the Institute of Professional Education, Moscow, Russia
)
Unerbaeva Saule (MD, director of the Joint somatics University Hospital №2 at KazNMU them. SD Asfendiyarov, Almaty, Kazakhstan)
Ilmalieva Aktoty ( Assistant of the Department of Endocrinology of the Joint University Hospital №2 at KazNMU them. SD Asfendiyarov, Almaty, Kazakhstan)
Petunina Nina ( MD, Professor, Head of the Department of Endocrinology
Institute of Vocational Education
I.M.Sechenov First Moscow State Medical University
)
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Evaluation of changes in the immune status of patients with comorbid course of thyroid disease and metabolic syndrome and their relationship to blood inflammatory reactions. In a comprehensive study of 90 patients at the age of 18 were included and older. The patients were divided into three groups: the core group - for comorbid metabolic syndrome and diseases of the thyroid gland, the comparison group - patients with complete and incomplete without the metabolic syndrome diagnosed have thyroid disease, patients with disorders of the thyroid gland without the metabolic syndrome.
the state of the immune status at study subjects consisted of phenotypic characteristics of immune cells of peripheral blood, determination of immunoglobulins, the calculation of the immunoregulatory index. It was found that the combined course of metabolic syndrome and thyroid gland cellular and humoral immunity characterized by stimulation of humoral immunity disimmunoglobulinemiey, lack of T-cell immunity that may be associated with chronic hyperinsulinemia, dyslipidemia and antigenic stimulation of lipoproteins that cause immunoinflammatory reactions .
The revealed changes of the immune status indicate the presence of autoimmune inflammatory reactions, indicating a higher risk of cardiovascular complications.
Keywords:Metabolic syndrome, thyroid disease, immune status, cardiovascular complications.
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Read the full article …
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Citation link:
Fateeva A. , Unerbaeva S. , Ilmalieva A. , Petunina N. Immunological reactions in patients comorbid flow in thyroid diseases and metabolic syndrome (complete or incomplete metabolic syndrome) // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2016. -№09-10. -С. 77-81 |
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