Rogozyanskaya Marina Igorevna (Applicant for a Degree at the Department of Oncology, FSBEI HE VSMU named after N.N. Burdenko, Oncologist at the Voronezh Regional Scientific and Clinical Oncology Center)
Redkin Alexander Nikolaevich (Doctor of Medical Sciences, Professor at the Department of Oncology, FSBEI HE VSMU named after N.N. Burdenko)
Alexander Ivanovich Zhdanov (Doctor of Medical Sciences, Professor at the Department of Specialized Surgical Disciplines, FSBEI HE VSMU named after N.N. Burdenko)
| |
Gastrectomy remains key for locally advanced gastric cancer (GC), yet complication rates (30%) and mortality (5%) remain high. Improved techniques and recovery programs haven’t fully resolved safety concerns, necessitating better risk assessment and personalized approaches.
Methods. This study identified risk factors for post-gastrectomy complications in 570 GC patients (stages IB–III). Results. Complications (Clavien-Dindo) included pancreatitis (2.6%), bleeding (1.6%), and anastomotic leak (0.6%). Grade 3–5 complications occurred in 6.6%, mortality in 1.6%. Significant predictors: ECOG >1 (↑risk 2.5–4.8×), splenopancreatic dissection (↑2.8×), T3–4 (↑2.6×), N+ (↑4.3×), and stage ≥IIIA. Conclusions: Modifiable factors (e.g., splenopancreatic dissection) must be weighed, but precise T/N staging requires histopathology. Preoperative staging (EUS, PET-CT) should be optimized for risk prediction. A multivariate predictive model is planned to assess cumulative risks.
Keywords:gastrectomy, splenopancreatic dissection, postoperative complications, risk factors
|
|
| |
|
Read the full article …
|
Citation link:
Rogozyanskaya M. I., Redkin A. N., Alexander I. Z. RISK FACTOR ANALYSIS FOR EARLY POSTOPERATIVE COMPLICATIONS FOLLOWING GASTRECTOMY IN GASTRIC CANCER PATIENTS // Современная наука: актуальные проблемы теории и практики. Серия: Естественные и Технические Науки. -2025. -№06. -С. 291-295 DOI 10.37882/2223-2966.2025.06.38 |
|
|
